Ensemble Deep Learning Object Detection Fusion for Cell Tracking, Mitosis, and Lineage

نویسندگان

چکیده

Cell tracking and motility analysis are essential for understanding multicellular processes, automated quantification in biomedical experiments, medical diagnosis treatment. However, manual is labor-intensive, tedious, prone to selection bias errors. Building upon our previous work, we propose a new deep learning-based method, EDNet, cell detection, tracking, that more robust shape across different lines, models lineage proliferation. EDNet uses an ensemble approach 2D detection deep-architecture-agnostic achieves state-of-the-art performance surpassing single-model YOLO FasterRCNN convolutional neural networks. detections used M2Track multiobject algorithm cells, detecting mitosis (cell division) events, graphs. Our methods produce on the Tracking Mitosis (CTMCv1) dataset with Multiple Object Accuracy (MOTA) score of 50.6% graph edit (TRA) 52.5%. Additionally, compare human external data studying muscle stem cells physiological molecular stimuli. We believe method has potential improve accuracy efficiency analysis. This could lead significant advances research diagnosis. code made publicly available GitHub 1 .

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ژورنال

عنوان ژورنال: IEEE open journal of engineering in medicine and biology

سال: 2023

ISSN: ['2644-1276']

DOI: https://doi.org/10.1109/ojemb.2023.3288470